Treatment with antipsychotics is a mainstay of trial competency restoration, particularly given that most defendants deemed incompetent to stand trial have psychotic illnesses. We explored the association between competency restoration and antipsychotic type in a retrospective sample of defendants diagnosed with psychotic disorders and deemed incompetent to stand trial. Using regression models, we calculated the odds ratio of being competent to stand trial, adjusting for relevant confounders. We found that the use of long-acting injectable antipsychotics was not significantly associated with increased odds of restoration of trial competency. Our results highlight the need for larger, longitudinal studies to further explore the efficacy and tolerability of long-acting injectable drugs compared with oral antipsychotics. Future research will help develop treatment guidelines within the setting of trial competency restoration.

中文翻译：

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长效注射剂与口服抗精神病药可恢复其胜任力。

抗精神病药的治疗是恢复审判能力的主要手段，特别是考虑到大多数被认为无能力接受审判的被告患有精神病。我们在回顾性样本中探讨了能力恢复与抗精神病类型之间的关联性，这些样本被诊断为患有精神病且被认为无能力接受审判。使用回归模型，我们可以计算出有能力受审并针对相关混杂因素进行调整的优势比。我们发现使用长效抗精神病药与恢复试验能力的几率没有显着相关。我们的结果强调需要进行更大的纵向研究，以进一步探索长效可注射药物与口服抗精神病药相比的疗效和耐受性。