A late detection of pathogenic microorganisms in food and drinking water has a high potential to cause adverse health impacts in those who have ingested the pathogens. For this reason there is intense interest in developing precise, rapid and sensitive assays that can detect multiple foodborne pathogens. Such assays would be valuable components in the campaign to minimize foodborne illness. Here, we discuss the emerging types of assays based on gold nanoparticles (GNPs) for rapidly diagnosing single or multiple foodborne pathogen infections. Colorimetric and lateral flow assays based on GNPs may be read by the human eye. Refractometric sensors based on a shift in the position of a plasmon resonance absorption peak can be read by the new generation of inexpensive optical spectrometers. Surface-enhanced Raman spectroscopy and the quartz microbalance require slightly more sophisticated equipment but can be very sensitive. A wide range of electrochemical techniques are also under development. Given the range of options provided by GNPs, we confidently expect that some, or all, of these technologies will eventually enter routine use for detecting pathogens in food. This article is categorized under: Diagnostic Tools > Biosensing.

中文翻译：

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通过金纳米颗粒测定法一次或多次检测食源性病原体。

对食物和饮用水中的病原微生物进行较晚的检测，很有可能对摄入病原体的人们造成不利的健康影响。因此，人们对开发可以检测多种食源性病原体的精确，快速和灵敏的测定法引起了极大的兴趣。这样的测定将是运动中减少食源性疾病的有价值的组成部分。在这里，我们讨论了基于金纳米颗粒（GNP）的新兴分析方法，它们可以快速诊断单个或多个食源性病原体感染。人眼可以读取基于GNP的比色和侧向流动分析。新一代廉价的光谱仪可以读取基于等离振子共振吸收峰位置发生变化的折光仪传感器。表面增强拉曼光谱和石英微量天平需要稍微复杂一些的设备，但可能非常敏感。各种各样的电化学技术也在开发中。鉴于GNP提供的选择范围很广，我们充满信心地期望这些技术中的某些或全部最终将进入常规用途以检测食物中的病原体。本文归类于：诊断工具>生物传感。