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Rethinking enzyme kinetics: Designing and developing a biomolecular interactive tutorial (BIOMINT) learning tool for undergraduate students
Biochemistry and Molecular Biology Education ( IF 1.2 ) Pub Date : 2019-09-18 , DOI: 10.1002/bmb.21302
Jerry Gu 1 , Stavroula Andreopoulos 2 , Jodie Jenkinson 1, 3 , Derek P Ng 1, 3
Affiliation  

Enzyme kinetics is the study of enzymatic catalytic rates in biochemical reactions. This topic is commonly taught to life science students in introductory biochemistry courses during their undergraduate education. Unlike most other biochemistry topics, which focus on visual structures of biomolecules and their processes, enzyme kinetics is explained primarily through abstract mathematical and two‐dimensional graphical plots. However, these abstract/symbolic representations often make it difficult for students to relate the kinetic parameters to the underlying molecular system that is being described. In this article, we present the design and development of a web‐based multimedia interactive learning tool, biomolecular interactive tutorials (BIOMINT) to help students better bridge the relationships between these abstract mathematical models and the molecular behaviors, interactions, and dynamics that produce kinetic phenomena. This learning tool can be accessed at https://bit.ly/biomint. © 2019 International Union of Biochemistry and Molecular Biology, 48(1):74–79, 2020.

中文翻译:

重新思考酶动力学:为本科生设计和开发生物分子互动教程 (BIOMINT) 学习工具

酶动力学是对生化反应中酶催化速率的研究。该主题通常在生命科学学生本科教育期间在介绍性生物化学课程中教授。与大多数关注生物分子及其过程的视觉结构的其他生物化学主题不同,酶动力学主要通过抽象的数学和二维图形来解释。然而,这些抽象/符号表示通常使学生难以将动力学参数与所描述的潜在分子系统联系起来。在本文中,我们介绍了基于 Web 的多媒体交互式学习工具的设计和开发,生物分子互动教程 (BIOMINT) 帮助学生更好地弥合这些抽象数学模型与产生动力学现象的分子行为、相互作用和动力学之间的关系。这个学习工具可以在 https://bit.ly/biomint 访问。© 2019 国际生物化学与分子生物学联盟,48(1):74–79,2020。
更新日期:2019-09-18
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