The rat palatine fissure is anatomically similar to human alveolar cleft. In this study, we examined potential bone repair by an autologous bone implant and beta-tricalcium phosphate (β-TCP) using rat palatine fissure as a model. Autologous bone chips or β-TCP granules were implanted into the rat palatine fissure. Our model demonstrated that higher bone volume and bone mineral density were achieved with autologous bone graft than with β-TCP. We have provided the first demonstration of the suitability of the rat palatine fissure as the implant site to simulate the transplantation of bone graft materials into human alveolar cleft.

中文翻译：

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大鼠Pala裂：评估骨再生的合适实验模型。

大鼠p裂在解剖学上与人牙槽裂相似。在这项研究中，我们以大鼠p裂为模型，通过自体骨植入物和β-磷酸三钙（β-TCP）检查了潜在的骨修复。自体骨屑或β-TCP颗粒被植入大鼠p裂中。我们的模型表明，自体植骨获得的骨体积和骨矿物质密度高于β-TCP。我们已经提供了大鼠p裂作为植入部位以模拟骨移植材料移植到人牙槽裂中的适合性的第一个证明。