OBJECTIVES To assess the value of a T1-3D black-blood turbo spin echo (TSE) sequence for the diagnosis of abdominal large vessel vasculitis (LVV). MATERIALS AND METHODS The study included 20 patients with abdominal LVV and 17 controls, who underwent a 3T-MRI scan using a modified T1-3D volumetric isotropic TSE acquisition and a segmented T1-3D turbo field echo sequence (T1-mVISTA/T1-eTHRIVE). Two radiologists independently analyzed the aorta for concentric contrast enhancement, concentric wall thickening, image quality, and flow artifact intensity (CCE/CWT/IQ/FAI; 4-point scales). The mean aortic wall thickness (MAWT) in post-contrast T1-mVISTA was compared between patients and controls. RESULTS IQ of T1-mVISTA was rated good to excellent in 91.5% of 282 evaluated vessel segments with no or minor FAI present in 85.5%. The inter-observer reproducibility for the identification of CCE/CWT on T1-mVISTA was 0.92 and 0.93 (p < 0.001). The distribution of segmental inflammation in T1-mVISTA significantly correlated with T1-eTHRIVE (CCE, κ = 0.768; CWT, κ = 0.715; p < 0.001), resulting in a sensitivity, specificity, and positive predictive value of 100%, 81.3%, and 83.3%. The MAWT significantly differed between patients and controls (3.29 ± 0.81 vs. 2.24 ± 0.45 mm; p < 0.001). CONCLUSIONS T1-mVISTA enables the evaluation of the MAWT and allows the detection of abdominal LVV. KEY POINTS • 3D T1w-mVISTA accurately depicted the large abdominal vessels. • 3D T1w-mVISTA enables accurate measurements of the abdominal aortic wall thickness. • 3D T1w-mVISTA is useful for the detection of abdominal LVV.

中文翻译：

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3D黑血3T-MRI诊断腹部大血管血管炎。

目的评估T1-3D黑血涡轮自旋回波（TSE）序列在诊断腹部大血管血管炎（LVV）中的价值。材料与方法这项研究包括20例腹部LVV患者和17例对照，他们使用改良的T1-3D体积各向同性TSE采集和分段的T1-3D涡轮场回波序列（T1-mVISTA / T1-eTHRIVE）进行了3T-MRI扫描）。两名放射科医生独立分析了主动脉的同心对比增强，同心壁增厚，图像质量和血流伪影强度（CCE / CWT / IQ / FAI； 4点标度）。在患者和对照组之间比较了T1-mVISTA造影剂后的平均主动脉壁厚度（MAWT）。结果在282个评估血管段的91.5％中，T1-mVISTA的智商被评为良好至极好，而FAI则为85.5％，FAI不存在或较小。观察者间在T1-mVISTA上鉴定CCE / CWT的再现性为0.92和0.93（p <0.001）。T1-mVISTA中节段性炎症的分布与T1-eTHRIVE显着相关（CCE，κ= 0.768; CWT，κ= 0.715; p <0.001），敏感性，特异性和阳性预测值为100％，81.3％ ，和83.3％。患者与对照组之间的MAWT有显着差异（3.29±0.81 vs. 2.24±0.45 mm； p <0.001）。结论T1-mVISTA可以评估MAWT，并可以检测腹部LVV。要点•3D T1w-mVISTA准确描绘了大型腹部血管。•3D T1w-mVISTA可以精确测量腹主动脉壁厚度。•3D T1w-mVISTA可用于检测腹部LVV。92和0.93（p <0.001）。T1-mVISTA中节段性炎症的分布与T1-eTHRIVE显着相关（CCE，κ= 0.768; CWT，κ= 0.715; p <0.001），敏感性，特异性和阳性预测值为100％，81.3％ ，和83.3％。患者与对照组之间的MAWT有显着差异（3.29±0.81 vs. 2.24±0.45 mm； p <0.001）。结论T1-mVISTA可以评估MAWT，并可以检测腹部LVV。要点•3D T1w-mVISTA准确描绘了大型腹部血管。•3D T1w-mVISTA可以精确测量腹主动脉壁厚度。•3D T1w-mVISTA可用于检测腹部LVV。92和0.93（p <0.001）。T1-mVISTA中节段性炎症的分布与T1-eTHRIVE显着相关（CCE，κ= 0.768; CWT，κ= 0.715; p <0.001），敏感性，特异性和阳性预测值为100％，81.3％ ，和83.3％。患者和对照组之间的MAWT有显着差异（3.29±0.81 vs. 2.24±0.45 mm； p <0.001）。结论T1-mVISTA可以评估MAWT，并可以检测腹部LVV。要点•3D T1w-mVISTA准确描绘了大型腹部血管。•3D T1w-mVISTA可以精确测量腹主动脉壁厚度。•3D T1w-mVISTA可用于检测腹部LVV。p <0.001），因此敏感性，特异性和阳性预测值分别为100％，81.3％和83.3％。患者与对照组之间的MAWT有显着差异（3.29±0.81 vs. 2.24±0.45 mm； p <0.001）。结论T1-mVISTA可以评估MAWT，并可以检测腹部LVV。要点•3D T1w-mVISTA准确描绘了大型腹部血管。•3D T1w-mVISTA可以精确测量腹主动脉壁厚度。•3D T1w-mVISTA可用于检测腹部LVV。p <0.001），因此敏感性，特异性和阳性预测值分别为100％，81.3％和83.3％。患者和对照组之间的MAWT有显着差异（3.29±0.81 vs. 2.24±0.45 mm； p <0.001）。结论T1-mVISTA可以评估MAWT，并可以检测腹部LVV。要点•3D T1w-mVISTA准确描绘了大型腹部血管。•3D T1w-mVISTA可以精确测量腹主动脉壁厚度。•3D T1w-mVISTA可用于检测腹部LVV。结论T1-mVISTA可以评估MAWT，并可以检测腹部LVV。要点•3D T1w-mVISTA准确描绘了大型腹部血管。•3D T1w-mVISTA可以精确测量腹主动脉壁厚度。•3D T1w-mVISTA可用于检测腹部LVV。结论T1-mVISTA可以评估MAWT，并可以检测腹部LVV。要点•3D T1w-mVISTA准确描绘了大型腹部血管。•3D T1w-mVISTA可以精确测量腹主动脉壁厚度。•3D T1w-mVISTA可用于检测腹部LVV。