Cystic echinococcosis is a worldwide zoonosis caused by the cestode Echinococcus granulosus. Two types of hydatid cysts occur in intermediate hosts: fertile cysts that generate protoscoleces from the germinal layer of the cyst, and infertile cysts that do not produce protoscoleces and are unable to continue the life cycle of the parasite. The adventitial layer, a host-derived fibrous capsule surrounding the hydatid cyst, is suggested to play an important role in local immune regulation during infection and in fertility of the cysts. Fasciola hepatica, another important parasite of cattle, induces a characteristic Th2-like immune response that could modulate the immune response against E. granulosus. Natural co-infection of both parasites is common in cattle, but no reports describe the local immune response against E. granulosus with F. hepatica infection in the same host. This study analyzed the number and distribution of T and B cells in the adventitial layer of liver and lung cysts and the relationship with cyst fertility and F. hepatica co-infection. T lymphocytes were the predominant cell type in the adventitial layer of infertile hydatid cysts and were more numerous in infertile hydatid cysts. B lymphocyte numbers were not associated with hydatid cyst fertility. Mast cells were infrequent in the adventitial layer. The number of T and B cells was not associated with F. hepatica co-infection. The present study contributes to the understanding of local immune responses in bovine cystic echinococcosis.

中文翻译：

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牛Hy虫囊囊表层的淋巴细胞群：与囊肿受精状况和Fasciola Hepatica合并感染的关系。

囊性棘球co虫病是一种世界范围的人畜共患病，是由est虫棘球E虫引起的。中间宿主中会出现两种类型的包虫囊肿：从囊肿的生发层产生原生菌落的可育囊肿，以及不产生原生菌落且无法继续寄生虫生命周期的不育囊肿。建议外膜层是围绕包虫囊肿的宿主来源的纤维囊，在感染过程中的局部免疫调节和囊肿的生育中起重要作用。牛Fasciola hepatica是牛的另一种重要寄生虫，可诱导特征性的Th2样免疫应答，可调节针对粒状大肠杆菌的免疫应答。两种寄生虫的自然共同感染在牛中很常见，但是没有报道描述针对粒状大肠杆菌和F的局部免疫反应。在同一宿主中感染肝炎。这项研究分析了肝和肺囊肿外膜层中T和B细胞的数量和分布，以及与囊肿育性和肝炎肝炎合并感染的关系。T淋巴细胞是不育不育hy虫囊肿外膜层的主要细胞类型，而在不育不育hy虫囊肿中则更多。B淋巴细胞数量与包虫囊肿的繁殖力无关。肥大细胞在外膜层很少见。T和B细胞的数量与肝炎霍乱杆菌共感染无关。本研究有助于了解牛囊性包虫病中的局部免疫反应。这项研究分析了肝和肺囊肿外膜层中T和B细胞的数量和分布，以及与囊肿育性和肝炎肝炎合并感染的关系。T淋巴细胞是不育不育hy虫囊肿外膜层的主要细胞类型，而在不育不育hy虫囊肿中则更多。B淋巴细胞数量与包虫囊肿的繁殖力无关。肥大细胞在外膜层很少见。T和B细胞的数量与肝炎霍乱杆菌共感染无关。本研究有助于了解牛囊性包虫病中的局部免疫反应。这项研究分析了肝和肺囊肿外膜层中T和B细胞的数量和分布，以及与囊肿育性和肝炎肝炎合并感染的关系。T淋巴细胞是不育不育hy虫囊肿外膜层的主要细胞类型，而在不育不育hy虫囊肿中则更多。B淋巴细胞数量与包虫囊肿的繁殖力无关。肥大细胞在外膜层很少见。T和B细胞的数量与肝炎霍乱杆菌共感染无关。本研究有助于了解牛囊性包虫病中的局部免疫反应。B淋巴细胞数量与包虫囊肿的繁殖力无关。肥大细胞在外膜层很少见。T和B细胞的数量与肝炎霍乱杆菌共感染无关。本研究有助于了解牛囊性包虫病中的局部免疫反应。B淋巴细胞数量与包虫囊肿的繁殖力无关。肥大细胞在外膜层很少见。T和B细胞的数量与肝炎霍乱杆菌共感染无关。本研究有助于了解牛囊性包虫病中的局部免疫反应。