当前位置:
X-MOL 学术
›
Cardiovasc. Eng. Technol.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Asymmetric Dynamics of the Native Aortic Annulus Evaluated by Force Transducer and Sonomicrometry in a Porcine Model.
Cardiovascular Engineering and Technology ( IF 1.6 ) Pub Date : 2019-06-07 , DOI: 10.1007/s13239-019-00418-1 Leila Louise Benhassen 1, 2 , Diana Mathilde Ropcke 1, 2 , Troels Lading 1, 2 , Jens Kæstel Skov 1, 2 , Tommy Bechsgaard 1, 2, 3 , Søren Nielsen Skov 1, 2 , Sten Lyager Nielsen 1, 2 , John Michael Hasenkam 1, 2
中文翻译:
在猪模型中通过力传感器和超声测量法评估的原生主动脉环的不对称动力学。
更新日期:2019-06-07
Cardiovascular Engineering and Technology ( IF 1.6 ) Pub Date : 2019-06-07 , DOI: 10.1007/s13239-019-00418-1 Leila Louise Benhassen 1, 2 , Diana Mathilde Ropcke 1, 2 , Troels Lading 1, 2 , Jens Kæstel Skov 1, 2 , Tommy Bechsgaard 1, 2, 3 , Søren Nielsen Skov 1, 2 , Sten Lyager Nielsen 1, 2 , John Michael Hasenkam 1, 2
Affiliation
Purpose
With new repair techniques of the aortic root and valve emerging, a detailed understanding of the dynamics of the aortic annulus and valve is required for optimal results. The objective of this study was to characterize geometrical changes and force distribution of the native porcine aortic annulus throughout the cardiac cycle.Methods
Measurements were performed in an acute 80 kg porcine model (n = 7) using sonomicrometry crystals in the aortic annulus for evaluation of geometry and dynamics, annular force transducer evaluating force distribution, and pressure measurements and echocardiography evaluating valve performance.Results
Overall, segmental force distribution and geometrical changes differed between different segments of the aortic annulus. The highest force development was found at the left/right interleaflet triangle (2.87 ± 2.1 N) and the largest segmental expansion was observed at the right-coronary and left-coronary sinus. The aortic annulus changed configuration throughout the cardiac cycle and became more oval in systole.Conclusions
This study is the first to describe detailed segmental dynamics and force distribution of the native aortic annulus in a porcine model in vivo. The heterogenous behavior of the aortic annulus suggests that different segments demand different support for repair of the aortic root and valve.中文翻译:
在猪模型中通过力传感器和超声测量法评估的原生主动脉环的不对称动力学。