Benzocaine is well-known for its role as an anesthetic agent and largely used in oral ulcers, ear pain and dental complications. Along with lidocaine and other local anesthetics, benzocaine has marked it as an anesthetic agent in surgical procedures and as Na+ channels blocker, as well. Analogues of benzocaine have been found to possess biological potentials including antibacterial, antifungal and anti-cancer. Some derivatives were found to have conspicuous action against tuberculosis. The current review focuses to explore the century-long potential of the molecule and its analogs that have appeared in the literature. Furthermore, highlighting the biological potential of benzocaine and its analogues shall open-up new dimensions of future research to design more potent analogues.

中文翻译：

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苯佐卡因：具有潜在药物的综述。

苯佐卡因作为麻醉剂而闻名，广泛用于口腔溃疡，耳痛和牙齿并发症。除利多卡因和其他局部麻醉剂外，苯佐卡因已将其标记为外科手术过程中的麻醉剂，同时也是Na +通道阻滞剂。已发现苯佐卡因的类似物具有生物学潜力，包括抗菌，抗真菌和抗癌作用。发现某些衍生物具有抗结核作用。本篇综述着重探讨文献中出现的这种分子及其类似物长达一个世纪的潜力。此外，强调苯佐卡因及其类似物的生物潜力将为未来研究设计更有效的类似物开辟新的领域。