BACKGROUND Paraquat (PQ) poisoning is a public health problem in many regions of Colombia. This study aimed to estimate the burden of PQ poisoning in the Department of Antioquia, Colombia. METHODS Disability-adjusted life year (DALYs) were calculated as the sum of years of life lost (YLL) and years of life lived with disability (YLD) due to paraquat poisoning in Antioquia; a bootstrapped method with 1000 iterations was used to estimate each statistical parameter using the package DALY calculator in R. For this instance, the annual incidence of paraquat poisoning was obtained from the reported surveillance data according to regional Government. RESULTS From 2010 to 2016, 3299 DALYs were estimated in the department of Antioquia for PQ intoxication, with a rate of 53.4 DALYs per 100,000 inhabitants. The majority of the DALYs (2852 DALYs) were generated for men ranging from 15 to 44 years old. CONCLUSION The rate of DALYs reported here is higher than that reported by all chemical poisonings. Better strategies to regulate and restrict the market of this dangerous products are required in Colombia.

中文翻译：

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哥伦比亚安蒂奥基亚省百草枯中毒的负担。

背景技术百草枯（PQ）中毒是哥伦比亚许多地区的公共卫生问题。这项研究旨在评估哥伦比亚安蒂奥基亚省的PQ中毒负担。方法残疾调整生命年（DALYs）的计算方法是因安蒂奥基亚州因百草枯中毒而导致的生命丧失年限（YLL）和残障生命年限（YLD）。使用R中的DALY计算器，使用具有1000次迭代的自举方法来估计每个统计参数。在这种情况下，根据地方政府的报告监测数据，得出了百草枯中毒的年发生率。结果从2010年到2016年，安蒂奥基亚省估计有3299个DALYs用于PQ中毒，每100,000居民中有53.4个DALYs。大多数DALY（2852 DALY）是针对15至44岁的男性而产生的。结论此处报道的DALYs发生率高于所有化学中毒报告的发生率。哥伦比亚需要更好的策略来规范和限制这种危险产品的市场。