PURPOSE The purpose of this study was to compare postoperative epithelial healing time and ocular discomfort score in patients wearing two types of silicon hydrogel bandage contact lenses (BCLs) following bilateral photorefractive keratectomy (PRK). METHODS For the study's contralateral eye comparison, 43 patients who underwent bilateral PRK were randomized to be fitted for a senofilcon a lens in one eye and a lotrafilcon B lens in the other. The patients were masked to the specific BCL in each eye. On the first 3 days after PRK, the epithelial defect size was calculated, and patients reported their level of ocular discomfort, including pain, epiphora, and photophobia, on a visual analog scale (0 = no pain or discomfort, 10 = highest level of pain and discomfort). RESULTS Epithelial defect size (mm2) did not differ significantly between the BCLs on Day 1 (senofilcon A vs. lotrafilcon B: 14.15 ± 5.59 vs. 14.93 ± 5.72, p = .327), Day 2 (senofilcon A vs. lotrafilcon B: 7.43 ± 4.67 vs. 7.04 ± 3.82, p = .586), or Day 3 (senofilcon A vs. lotrafilcon B: 0.59 ± 1.44 vs. 0.38 ± 1.08, p = .348) postoperation. By Day 3, re-epithelialization was complete in 35 eyes (81.3%) with senofilcon A lenses and 36 eyes (83.7%) with lotrafilcon B lenses. Patients reported less pain in eyes with senofilcon A lenses during the first 3 days postoperation (for all, p < .001) and less epiphora during the first 2 days postoperation (Day 1: p =  .008, Day 2: p <  .001, Day 3: p = .267) than in eyes with lotrafilcon B lenses. No significant difference in photophobia emerged between the BCLs postoperatively (for all, p > .05). CONCLUSIONS Although duration of corneal re-epithelialization after PRK between the two BCLs did not differ significantly, senofilcon A lenses caused significantly less pain and epiphora after PRK.

中文翻译：

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Senofilcon A和lotrafilcon B绷带隐形眼镜对双侧屈光性角膜切除术后上皮愈合和疼痛处理的影响。

目的本研究的目的是比较双侧屈光性角膜切除术（PRK）后戴两种类型的硅水凝胶绷带隐形眼镜（BCL）的患者的术后上皮愈合时间和眼部不适评分。方法为了进行本研究的对侧眼比较，随机将43例接受双侧PRK的患者的一只眼配戴Senofilcon A晶状体，另一只眼配用Lotrafilcon B晶状体。患者的每只眼睛都被屏蔽了特定的BCL。PRK术后的前三天，计算上皮缺损的大小，并以视觉模拟量表报告患者的眼部不适水平，包括疼痛，癫痫和畏光（0 =无疼痛或不适，10 =最高水平）。疼痛和不适）。结果在第1天的第2天（senofilcon A与lotrafilcon B：14.15±5.59 vs. 14.93±5.72，p = .327）之间，BCL之间的上皮缺损大小（mm2）没有显着差异（第2天（senofilcon A与lotrafilcon B的对比）：手术后第7.43±4.67 vs.7.04±3.82，p = .586）或第3天（senofilcon A vs.lotrafilcon B：0.59±1.44 vs.0.38±1.08，p = .348）。到第3天，使用senofilcon A晶状体的35眼（81.3％）和使用lotrafilcon B晶状体的36眼（83.7％）完成了上皮再形成。患者在手术后前3天内报告使用senofilcon A晶状体的眼睛疼痛减轻（所有情况，p <.001），在手术后前2天（第1天：p = .008，第2天：p <.001 ，第3天：p = .267）。术后各BCL之间的畏光没有显着差异（对所有人而言，p> .05）。