The adaptogenic properties of alkylglycerols (AGs) after 1 month's treatment were investigated in a rat model of acute immobilization stress (AIS). The animals receiving AGs 157 mg/kg showed a body weight (BW) decrease in addition to a more pronounced increase in the adrenal glands index under stress conditions. Also, AGs at this dose prevented AIS-induced catalase inhibition. In addition, antiulcerative AG effects were already detected at a dose of 15 mg/kg. The data indicate that AGs promote adrenal gland activation in AIS. At the same time, AGs neutralize some of negative effects of stressful conditions, which include restoration of the oxidation-reduction balance, reduction of gastric mucosal stress lesion formation.LAY SUMMARYThe effect of alkylglycerols, ether lipids from marine organisms, was studied in stressed animals. AGs have antioxidant activity and can be useful in the complex therapy of stomach lesions.

中文翻译：

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烷基甘油在压力下的保护作用。

在急性固定应激（AIS）大鼠模型中研究了烷基甘油（AGs）在治疗1个月后的适应能力。接受AGs 157 mg / kg的动物在压力条件下除了肾上腺指数显着增加外，还表现出体重（BW）降低。同样，该剂量的AG阻止了AIS诱导的过氧化氢酶抑制。另外，已经以15mg / kg的剂量检测到抗溃疡的AG作用。数据表明AG可以促进AIS中的肾上腺激活。同时，AGs中和了一些应激条件的负面影响，包括恢复氧化还原平衡，减少胃粘膜应激损伤的形成。LAY Summary在应激动物中研究了烷基甘油，海洋生物的醚脂质的影响。 。