Objectives. Certain studies have claimed that borderline personality disorder (BPD) could be evaluated as a subtype of bipolar disorder (BD), whereas others have argued that BPD should be regarded as an independent disorder because of its distinct clinical features. The aim of this study was to investigate if there was a difference between these 2 disorders biologically based on EEG recordings. Methods. A total of 111 subjects (11 healthy, 25 BPD, 75 BD) who had resting EEG recordings were included. The EEGs were analyzed to compute absolute power values. Results. One-way analysis of variance results revealed statistically significant differences among the 3 groups on 55 out of 229 EEG variables. However, post hoc analysis indicated that all of the significant changes were between healthy and patient groups and no significant differences were found between 2 clinical groups. Conclusion. The findings suggested that these 2 clinical entities are biologically similar; however, further research should be performed to explain the basis clinical differences between the 2 disorders.

中文翻译：

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无法从电生理上区分边缘型人格和双相情感障碍

目标。某些研究声称边缘型人格障碍 (BPD) 可以被评估为双相情感障碍 (BD) 的一种亚型，而其他研究则认为 BPD 应被视为一种独立的疾病，因为它具有独特的临床特征。本研究的目的是根据 EEG 记录调查这两种疾病在生物学上是否存在差异。方法。共有 111 名受试者（11 名健康，25 BPD，75 BD）进行了静息脑电图记录。分析 EEG 以计算绝对功率值。结果。方差结果的单向分析显示，3 组之间在 229 个 EEG 变量中的 55 个具有统计学显着差异。然而，事后分析表明，所有显着变化都发生在健康组和患者组之间，两个临床组之间没有发现显着差异。结论。研究结果表明，这两个临床实体在生物学上是相似的；然而，应该进行进一步的研究来解释这两种疾病之间的基本临床差异。