The development of pharmaceutical analytical methods represents one of the most significant aspects of drug development. Recent advances in microfabrication and microfluidics could provide new approaches for drug analysis, including drug screening, active testing and the study of metabolism. Microfluidic chip technologies, such as lab-on-a-chip technology, three-dimensional (3D) cell culture, organs-on-chip and droplet techniques, have all been developed rapidly. Microfluidic chips coupled with various kinds of detection techniques are suitable for the high-throughput screening, detection and mechanistic study of drugs. This review highlights the latest (2010–2018) microfluidic technology for drug analysis and discusses the potential future development in this field.

药物分析方法的开发代表了药物开发的最重要方面之一。微加工和微流控技术的最新进展可以为药物分析提供新方法，包括药物筛选，主动检测和代谢研究。微流体芯片技术，例如芯片实验室技术，三维（3D）细胞培养，芯片上器官和液滴技术，都得到了快速发展。微流体芯片与各种检测技术相结合，适用于药物的高通量筛选，检测和机理研究。这篇综述重点介绍了用于药物分析的最新（2010–2018）微流体技术，并讨论了该领域的潜在未来发展。