In recent decades, chemical protein synthesis and the development of chemoselective reactions—including ligation reactions—have led to significant breakthroughs in protein science. Among them are a better understanding of protein structure‐function relationships, the study of protein posttranslational modifications, exploration of protein design, unnatural amino acid incorporation, and the study of therapeutic proteins and protein folding. Chalcogen chemistry, especially that of sulfur and selenium, is quite rich, and we have witnessed continuous progress in this field in recent years. In this short review, we will instead summarize three stories that we have recently presented on chalcogen chemistry and its impact on protein science, which was presented in the Miklós Bodanszky Award Lecture at the 35th European Peptide Society Meeting in Dublin, Ireland, 26 August 2018.

中文翻译：

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MiklósBodanszky奖演讲：研究蛋白质科学的选择性硫属化学。

近几十年来，化学蛋白质合成和化学选择性反应（包括连接反应）的发展已在蛋白质科学领域取得了重大突破。其中包括对蛋白质结构-功能关系的更好理解，对蛋白质翻译后修饰的研究，对蛋白质设计的探索，非天然氨基酸掺入以及对治疗性蛋白质和蛋白质折叠的研究。硫属元素化学，尤其是硫和硒，非常丰富，近年来，我们见证了这一领域的不断发展。在这篇简短的评论中，我们将总结最近发表的关于硫属元素化学及其对蛋白质科学的影响的三个故事，这些故事在都柏林第35届欧洲肽学会会议的MiklósBodanszky奖演讲中进行了介绍，