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Fertility in testicular cancer patients: a single-centre study in Turkey.
International Journal of Clinical Oncology ( IF 2.4 ) Pub Date : 2019-08-26 , DOI: 10.1007/s10147-019-01534-7
Mürvet Artuk Uçar 1 , Fatma Arikan 2 , Hasan Şenol Coşkun 3 , Yasemin Kondak 1 , Ali Murat Tatlı 3 , Sema Sezgin Göksu 3
Affiliation  

BACKGROUND Testicular cancer is a rare type of cancer in males. Since the disease is seen in young men and long-term survival is ensured following a high treatment success rate, fertility in testicular cancer patients is much more important. Prior to commencement of cancer treatment, patients are given counselling with regard to infertility and sexual function, and sperm banking is commonly carried out. The aim of this study was to assess the fertility status prior to and following treatment of monitored testicular cancer patients whose treatment had been completed. METHODS 110 patients diagnosed with and treated for testicular cancer at the Medical Oncology Clinic at Akdeniz University during the years 2000-2016 were evaluated for the study. The patients' disease and treatment information was obtained from their records. The patients' characteristics and fertility statuses were determined by means of interviews with the patients. RESULTS The median age of the patients was 36 (20-73) and 39.1% of them (n = 43) were aged between 30 and 39. The average length of follow-up was 6.20 ± 3.36 (2-17) years. It was determined that 42.7% of the patients had banked sperm following diagnosis and that 74.5% of them had received counselling. Following treatment, 33 patients (30%) fathered children. The average time taken to father children after treatment was 3 years. CONCLUSION In testicular cancer patients, fatherhood is achieved spontaneously or with the cryopreservation process. Counselling plays an important role at the time of diagnosis. It is essential that health professionals in oncology clinics give counselling about fertility in testicular cancer.

中文翻译:

睾丸癌患者的生育能力:土耳其的单中心研究。

背景技术睾丸癌是男性中罕见的癌症。由于该疾病在年轻人中可见,并且在高治疗成功率之后可确保长期存活,因此睾丸癌患者的生育能力更为重要。在开始癌症治疗之前,会为患者提供有关不育和性功能的咨询,并且通常进行精子保存。这项研究的目的是评估已完成治疗的受监测睾丸癌患者治疗前后的生育状况。方法对2000-2016年在阿克德尼兹大学医学肿瘤诊所诊断并治疗过睾丸癌的110名患者进行研究。从他们的记录中获得患者的疾病和治疗信息。患者的 通过与患者的访谈来确定特征和生育状况。结果患者的中位年龄为36岁(20-73),其中39.1%(n = 43)年龄在30至39岁之间。平均随访时间为6.20±3.36(2-17)岁。确诊后,有42.7%的患者患有精子堆积,其中74.5%的患者接受了咨询。治疗后,有33名患者(30%)育出孩子。治疗后生父的平均时间为3年。结论在睾丸癌患者中,父性是自发的或通过冷冻保存过程实现的。在诊断时,咨询起着重要的作用。肿瘤诊所的卫生专业人员必须就睾丸癌的生育能力提供咨询。
更新日期:2020-02-27
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