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New Metaphors for New Understandings of Genomes
Perspectives in Biology and Medicine ( IF 0.8 ) Pub Date : 2019-01-01 , DOI: 10.1353/pbm.2019.0000
Sarah Tinker Perrault , Meaghan O'Keefe

abstract:New techniques have made genome modification cheaper, easier, and faster, leading to a boom in research, especially for biomedical uses. Given the scope and potential power of this research and its applications, people need accurate information about what is being done or proposed, and why, and what the social and political implications might be. Metaphors can be useful in explaining complex topics, as they present the new in terms of the familiar. However, they can also misrepresent both how genomes and bodies work and the social and political implications of research and applications. Existing research shows that this is happening and that we need new language. However, it is not always easy to decide whether an alternative does rhetorical work that will empower publics, patients, biologists, and physicians alike. This article offers a conceptual framework for developing, analyzing, critiquing, and choosing new metaphors that will help improve communication about genomes and genomic research.

中文翻译:

对基因组新理解的新隐喻

摘要:新技术使基因组修饰更便宜、更容易、更快捷,导致研究热潮,尤其是在生物医学用途方面。鉴于这项研究及其应用的范围和潜在力量,人们需要关于正在做或提议的内容、原因以及可能产生的社会和政治影响的准确信息。隐喻可用于解释复杂的主题,因为它们以熟悉的方式呈现新事物。然而,它们也可能歪曲基因组和身体的工作方式以及研究和应用的社会和政治影响。现有研究表明,这种情况正在发生,我们需要新的语言。然而,要决定一种替代方案是否能够为公众、患者、生物学家和医生等人赋能,并不总是那么容易。
更新日期:2019-01-01
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