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Do Upper and Lower Camptocormias Affect Gait and Postural Control in Patients with Parkinson's Disease? An Observational Cross-Sectional Study.
Parkinson's Disease ( IF 3.2 ) Pub Date : 2019-07-24 , DOI: 10.1155/2019/9026890
Christian Geroin 1, 2 , Marialuisa Gandolfi 2, 3 , Isacco Maddalena 3 , Nicola Smania 2, 3 , Michele Tinazzi 1, 2
Affiliation  

Gait impairments and camptocormia (CC) are common and debilitating in patients with Parkinson’s disease (PD). Two types of CC affect patients with PD, but no studies investigated their relative contribution in worsening gait and postural control. Therefore, we investigated spatiotemporal gait parameters, gait variability, and asymmetry and postural control in PD patients (Hoehn & Yahr ≤4) with upper CC and lower CC and patients without CC. This observational cross-sectional study involving patients with PD and upper CC () and lower CC () and without CC (). The primary outcome measure was gait speed assessed by the GAITRite System. The secondary outcome measures were other spatiotemporal parameters, gait variability, and asymmetry. Postural control and balance were assessed with posturography and the Mini-BESTest. Patients with lower CC showed a higher H&Y stage (), a worse PDQ8 (), and a lower Mini-BESTest score () than patients with PD without CC. Patients with lower CC showed a reduced gait speed (), stride length, and velocity than patients with PD without CC. Upper CC patients showed a higher stride length than lower CC ones (). In the eyes open and closed condition, patients with lower CC showed a higher (worse) velocity of CoP displacement in mediolateral direction and length of CoP than patients with PD without CC. No significant between-group differences were measured in gait variability and asymmetry. In conclusion, lower CC was associated with more severe gait and postural control impairment than patients with upper CC and without CC. Categorizing CC based on the bending fulcrum is compulsory to identify patients with the worst performance and to implement specific rehabilitation programs.

中文翻译:

帕金森氏病患者的上,下Camtopcormias是否影响步态和姿势控制?观察性横断面研究。

帕金森病(PD)患者的步态障碍和喜树皮病(CC)很常见,并且使人衰弱。两种类型的CC影响PD患者,但没有研究调查他们在步态恶化和姿势控制方面的相对作用。因此,我们研究了上CC和下CC以及无CC的PD患者(Hoehn&Yahr≤4)的时空步态参数,步态变异性,不对称性和姿势控制。这项观察性横断面研究涉及具有PD和上CC(和下CC(而无CC()的患者主要结果指标是由GAITRite系统评估的步态速度。次要结局指标是其他时空参数,步态变异性和不对称性。使用姿势描记法和Mini-BESTest评估姿势控制和平衡。与没有CC的PD患者相比,具有较低CC的患者表现出较高的H&Y分期(),较差的PDQ8(和较低的Mini-BESTest得分(。与没有CC的PD患者相比,具有较低CC的患者的步态速度(),步幅和速度降低。高位CC患者的步幅比低位CC患者高()。在睁开和闭眼的情况下,CC较低的患者与没有CC的PD患者相比,CoP沿中外侧方向的CoP移位速度(更差)和CoP长度更高。在步态变异性和不对称性方面未观察到明显的组间差异。总之,与没有CC的高CC患者相比,较低的CC与更严重的步态和姿势控制障碍相关。必须根据弯曲支点对CC进行分类,以识别表现最差的患者并实施特定的康复计划。
更新日期:2019-07-24
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