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The paleoepidemiology of Sacral Spina Bifida Occulta in population samples from the Dakhleh Oasis, Egypt.
International Journal of Paleopathology ( IF 1.3 ) Pub Date : 2019-07-24 , DOI: 10.1016/j.ijpp.2019.06.006
Joseph E Molto 1 , Casey L Kirkpatrick 1 , James Keron 1
Affiliation  

Objective

To document sacral spina bifida occulta (SSB0) prevalence in a population sample from the Dakhleh Oasis, Egypt, and address methodological issues in recording and quantifying SSBO variations.

Materials

442 adult sacra from two temporally disjunct samples from the same deme traversing the 3rd intermediate (TIP) and the Roman Periods.

Methods

Sacra were scored for SSBO, excluding the sacral hiatus. Risk of SSBO was calculated with the common odds ratio and statistical significance by X2. Data were compared to other archaeological SSBO data.

Results

SSBO was present in 15.6% of the sample with a slight, but not significant, temporal increase (TIP to Roman Period) in males, and a significant age-correlated increase in both sexes. Most open sacra occurred in young adults.

Conclusions

Data support that SSBO can be considered as a morphogenetic variant. Dakhleh data fall within the prevalence range for most populations, however inter-population comparisons are complicated by methodological inconsistencies.

Significance

SSBO can be used in paleogenetic research.

Limitations

Methodological differences in scoring SSBO prevent effective comparative study.

Suggested future research

Future studies require more rigorous and standardized scoring methods. aDNA may be used to corroborate the morphogenetic value of SSBO and determine its clinical significance.



中文翻译:

埃及达赫勒绿洲种群样本中S骨脊柱裂的隐匿性古流行病学。

目的

要记录来自埃及达赫勒绿洲的人群样本中的spin骨脊柱隐匿性(SSB0)患病率,并解决记录和量化SSBO变异的方法学问题。

用料

442个成年sa骨,来自两个跨过第三中间(TIP)和罗马时期的同一地点的时间分离样本。

方法

cra骨得分为SSBO,不包括the裂。用X 2的共同优势比和统计显着性计算SSBO的风险。将数据与其他考古SSBO数据进行比较。

结果

样本中SSBO的含量为15.6%,男性略有但不显着的暂时性增加(到罗马时期的TIP),并且与性别相关的年龄也显着增加。多数开放sa骨发生在年轻人中。

结论

数据支持认为SSBO可被视为形态发生变体。Dakhleh数据在大多数人群的流行范围内,但是方法间的不一致使人群间的比较变得复杂。

意义

SSBO可用于古生物学研究。

局限性

SSBO评分方法上的差异阻碍了有效的比较研究。

建议的未来研究

未来的研究需要更严格和标准化的评分方法。aDNA可用于证实SSBO的形态发生价值,并确定其临床意义。

更新日期:2019-07-24
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