The human immunodeficiency virus (HIV-1 virus) exploits several host factors for assembly, infection, and replication within the infected cells. In this work, we describe the evidence for an interaction of the N-terminal domain of the HIV-1 capsid protein with human calmodulin. The precise role of this interaction within the life cycle of the HIV-1 virus is yet to be defined. Potential roles for this interaction in the viral capsid uncoating are discussed.

中文翻译：

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HIV-1病毒与宿主蛋白的相互作用：HIV-1衣壳蛋白的N末端域与人钙调蛋白的相互作用。

人类免疫缺陷病毒（HIV-1病毒）利用几种宿主因子在感染细胞内进行组装，感染和复制。在这项工作中，我们描述了HIV-1衣壳蛋白N末端域与人钙调蛋白相互作用的证据。这种相互作用在HIV-1病毒生命周期中的确切作用尚待确定。讨论了这种相互作用在病毒衣壳脱膜中的潜在作用。