Genetically encoded, single-component optogenetic tools have made a significant impact on neuroscience, enabling specific modulation of selected cells within complex neural tissues. As the optogenetic toolbox contents grow and diversify, the opportunities for neuroscience continue to grow. In this review, we outline the development of currently available single-component optogenetic tools and summarize the application of various optogenetic tools in diverse model organisms.

中文翻译：

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光遗传学的发展与应用。

基因编码的单组分光遗传学工具对神经科学产生了重大影响，能够对复杂神经组织内的选定细胞进行特定调节。随着光遗传学工具箱内容的增长和多样化，神经科学的机会不断增加。在这篇综述中，我们概述了目前可用的单组分光遗传学工具的发展，并总结了各种光遗传学工具在不同模式生物中的应用。