OBJECTIVE  The aim of this study was to evaluate the biomechanical properties of three different miniature locking plate systems used to fixate radial and ulnar fractures in toy breed dogs. Implant size, shape, material and locking systems differ, and their influence on the fracture healing process is unknown. In the present study, we aimed to investigate this matter in vivo using rabbit radial and ulnar fracture models. STUDY DESIGN  Eighteen rabbits were randomly divided into three groups, and the left radius and ulna were osteotomized to create fracture models. The osteotomies were then fixated using either the TITAN LOCK 1.5, Fixin micro or LCP 1.5 system. Radiographs were obtained 2, 3 and 4 weeks after surgery. Four weeks after surgery, the radiuses were collected and used for biomechanical testing or histological examinations. RESULTS  During the 4 weeks of observation, no adverse effects due to the implants occurred. The radiographic scores in each group did not differ significantly at any time point. The maximum load in the LCP group was significantly higher than that in the TITAN and Fixin groups. There was no significant difference in bending stiffness or work to failure among the groups. Initial fracture healing via woven bone was evident at histological evaluation. CONCLUSIONS  All three miniature locking plate systems provided adequate fracture stabilization 4 weeks after surgery, despite their differences, in rabbit models.

中文翻译：

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兔Rad骨和尺骨骨折模型中三种微型锁定板系统的生物力学比较。

目的本研究的目的是评估用于固定玩具犬的dog骨和尺骨骨折的三种不同的微型锁定板系统的生物力学特性。植入物的大小，形状，材料和锁定系统不同，并且它们对骨折愈合过程的影响尚不清楚。在本研究中，我们旨在使用兔radial骨和尺骨骨折模型在体内研究此问题。研究设计将18只兔随机分为三组，将radius骨和尺骨切骨以创建骨折模型。然后使用TITAN LOCK 1.5，Fixin micro或LCP 1.5系统固定截骨术。在手术后2、3和4周获得射线照相。手术后四周，收集半径并用于生物力学测试或组织学检查。结果在观察的4周内，未发生因植入物引起的不良反应。每组的射线照相评分在任何时间点均无显着差异。LCP组的最大负荷明显高于TITAN和Fixin组。各组之间的弯曲刚度或破坏功没有显着差异。在组织学评估中，通过编织骨的初始骨折愈合是明显的。结论在兔模型中，尽管它们存在差异，所有三个微型锁定板系统均在术后4周提供了足够的骨折稳定度。LCP组的最大负荷明显高于TITAN和Fixin组。各组之间的弯曲刚度或破坏功没有显着差异。在组织学评估中，通过编织骨的初始骨折愈合是明显的。结论在兔模型中，尽管它们存在差异，所有三个微型锁定板系统均在术后4周提供了足够的骨折稳定度。LCP组的最大负荷明显高于TITAN和Fixin组。各组之间的弯曲刚度或破坏功没有显着差异。在组织学评估中，通过编织骨的初始骨折愈合是明显的。结论在兔模型中，尽管它们存在差异，所有三个微型锁定板系统均在术后4周提供了足够的骨折稳定度。