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Chemical shift assignments of retinal guanylyl cyclase activating protein 5 (GCAP5).
Biomolecular NMR Assignments ( IF 0.8 ) Pub Date : 2019-01-31 , DOI: 10.1007/s12104-019-09877-y
Diana Cudia 1 , James B Ames 1
Affiliation  

Retinal membrane guanylyl cyclase (RetGC) in photoreceptor rod and cone cells is regulated by a family of guanylyl cyclase activating proteins (GCAP1-7). GCAP5 is expressed in zebrafish photoreceptors and promotes Ca2+-dependent regulation of RetGC enzymatic activity that regulates visual phototransduction. We report NMR chemical shift assignments of the Ca2+-free activator form of GCAP5 (BMRB No. 27705).

中文翻译:

视网膜鸟苷酸环化酶激活蛋白 5 (GCAP5) 的化学位移分配。

感光杆细胞和视锥细胞中的视网膜膜鸟苷酸环化酶 (RetGC) 受鸟苷酸环化酶激活蛋白 (GCAP1-7) 家族的调控。GCAP5 在斑马鱼光感受器中表达并促进RetGC 酶活性的Ca 2+依赖性调节,调节视觉光转导。我们报告了 GCAP5 (BMRB No. 27705)的无 Ca 2+激活剂形式的NMR 化学位移分配。
更新日期:2019-01-31
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