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Petrous apex non-secretory plasma cell myeloma with aberrant cytokeratin expression
Journal of Histotechnology ( IF 0.6 ) Pub Date : 2019-08-19 , DOI: 10.1080/01478885.2019.1650998
Mohamed Badr-El-Dine 1 , Eman Abdelzaher 2 , Mohamed Eid 3 , Rawda Elshennawy 2
Affiliation  

ABSTRACT Multiple myeloma is a monoclonal proliferation of plasma cells with common involvement of vertebrae, ribs and skull vault. However, involvement of skull base is relatively uncommon and myeloma manifesting initially as a petrous apex mass is distinctly rare. We report a rare case of non-secretory multiple myeloma in a 52-year-old Egyptian male presenting primarily as a right petrous apex mass with abducens nerve palsy. Additionally, neoplastic cells aberrantly expressed cytokeratin. Although rare, plasma cell myeloma should be considered in the differential diagnosis of petrous apex masses.

中文翻译:

具有异常细胞角蛋白表达的岩尖非分泌性浆细胞骨髓瘤

摘要 多发性骨髓瘤是浆细胞的单克隆增殖,常见于椎骨、肋骨和颅顶。然而,颅底受累相对少见,最初表现为岩尖肿块的骨髓瘤明显罕见。我们报告了一例罕见的非分泌性多发性骨髓瘤病例,患者为 52 岁埃及男性,主要表现为右岩尖肿块伴外展神经麻痹。此外,肿瘤细胞异常表达细胞角蛋白。尽管罕见,但在岩尖肿块的鉴别诊断中应考虑浆细胞骨髓瘤。
更新日期:2019-08-19
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