Postprandial hyperglycemia is a known risk factor for the development of several health disorders, including type 2 diabetes, obesity and cardiovascular disease. This study aimed to investigate the acute effect of Undaria pinnatifida (Wakame), a discriminative constituent of the Japanese diet, on postprandial blood glucose and insulin levels. The study was conducted using a crossover method among 26 subjects. Blood was sampled for glucose and insulin measurements at 0, 30, 60, 90 and 120 min after a subject consumed either 200 g of rice or 200 g rice with 4 g of dried wakame. Blood glucose and insulin levels were significantly lower at 30 min after consuming rice with wakame than after consuming rice alone. Moreover, the incremental areas under the curves for glucose and insulin were lower when wakame was included. Wakame intake can improve postprandial glucose homeostasis. Wakame intake may offer a simple behavioural strategy that can reduce glycemic excursions in prediabetes. This study was registered with the UMIN Clinical Trial Registry (UMIN000031050).

中文翻译：

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裙带菜（裙带菜）对人类餐后血糖和胰岛素水平的影响：随机交叉试验


餐后高血糖是导致多种健康疾病的已知危险因素，包括 2 型糖尿病、肥胖和心血管疾病。本研究旨在调查裙带菜（裙带菜）（日本饮食中的一种特殊成分）对餐后血糖和胰岛素水平的急性影响。该研究采用交叉法在 26 名受试者中进行。在受试者食用 200 克大米或 200 克大米加 4 克干裙带菜后 0、30、60、90 和 120 分钟，采集血液样本进行葡萄糖和胰岛素测量。与单独食用米饭相比，食用裙带菜米饭后 30 分钟的血糖和胰岛素水平显着降低。此外，当包括裙带菜时，葡萄糖和胰岛素曲线下的增量面积较低。裙带菜摄入可以改善餐后血糖稳态。裙带菜的摄入可能提供一种简单的行为策略，可以减少糖尿病前期的血糖波动。该研究已在 UMIN 临床试验登记处注册 (UMIN000031050)。