In July 2018, the 11th Zebrafish Disease Models Conference (ZDM11) was held at Leiden University, The Netherlands, providing an excellent international opportunity for scientific presentations and collaborative discussion regarding the modeling of disease using zebrafish. Much like the original ZDM1, which was also hosted in Leiden in 2007, immunology and cancer had a strong presence at ZDM11, with zebrafish still proving an invaluable tool to interrogate their disease genetics and progression in vivo. In addition, ZDM11 built upon the inclusion and development of other key areas making use of zebrafish disease models, with sessions on neuroscience, behavior, muscle, skeletal and cardiac disease, and more. ZDM11 also highlighted the rapid progression and application of new and exciting technologies to assist in the generation and analysis of zebrafish disease models, including Crispr/Cas9 gene targeting tools, electroporation techniques, computational analysis, drug screening pipelines, and advances in vivo imaging such as high-resolution correlative electron microscopy and lightsheet microscopy. Here, we provide a summary of the ZDM11 conference proceedings, giving an overview of the stimulating science presented across 4 days and 13 conference sessions.

中文翻译：

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2018年在莱顿举行的第11届斑马鱼疾病模型会议。

2018年7月，第11届斑马鱼疾病模型会议（ZDM11）在荷兰的莱顿大学举行，为有关使用斑马鱼进行疾病建模的科学演示和协作讨论提供了绝佳的国际机会。与最初于2007年在莱顿（Leiden）举办的ZDM1一样，免疫学和癌症在ZDM11上也占有重要地位，斑马鱼仍被证明是在体内询问其疾病遗传和进展的宝贵工具。此外，ZDM11利用斑马鱼疾病模型，在其他关键领域的纳入和发展基础上，举办了有关神经科学，行为，肌肉，骨骼和心脏疾病等方面的会议。ZDM11还着重介绍了令人兴奋的新技术的快速发展和应用，以协助斑马鱼疾病模型的生成和分析，包括Crispr / Cas9基因靶向工具，电穿孔技术，计算分析，药物筛选流程以及诸如高分辨率相关电子显微镜和光片显微镜。在这里，我们提供了ZDM11会议程序的摘要，并概述了为期4天和13个会议会议中提出的刺激科学。