The manuscript published by Microb Biotechnol, volume 10, highlights the relevance of the fungus Nigrospora sphaerica, an endophyte isolated from Catharanthus roseus, as an alternative source to obtain vinblastine, a compound used in chemotherapy schemes to treat several types of cancer. Authors showed that purification of vinblastine from extracts of the fungus has higher activity and yield in comparison with that obtained from the plant Catharanthus roseus. This work represents a biotechnological approach to obtain vinblastine with promising results to decrease the production cost.

中文翻译：

---

生产抗癌的经济化合物的重要性。

Microb Biotechnol出版的手稿，第10卷着重强调了从长春花属植物中分离出的内生真菌Nigrospora sphaerica真菌的相关性，作为获取长春碱的替代来源，长春碱是一种用于化学疗法中治疗多种类型癌症的化合物。作者表明，与从长春花属植物中提取的长春花碱相比，从真菌提取物中纯化长春碱具有更高的活性和产量。这项工作代表了一种获得长春碱的生物技术方法，并有望降低生产成本。