ABSTRACT Wilhelm Bernhard’s revolutionary microscopy techniques helped him put forward the hypothesis of specialized compartmentalization of the nucleus. He also described for the first time the nuclear bodies and peri-chromatin fibrils, and demonstrated that these granules contain an RNA component. The tradition of biennial workshops, named after this great scientist, continues, and this year it took place in the heart of Burgundy, in Dijon, France (May 20–24, 2019, organized by INSERM UMR1231, UBFC), where well-fed participants emphasized the importance of viewing the cell nucleus as a hub of specialized colloidal compartments that orchestrate replication, transcription and nuclear transport.

中文翻译：

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细胞核。勃艮第的研究

摘要 Wilhelm Bernhard 革命性的显微镜技术帮助他提出了细胞核专门区室化的假设。他还首次描述了核体和染色质周围原纤维，并证明这些颗粒含有 RNA 成分。以这位伟大科学家的名字命名的两年一度的研讨会的传统仍在继续，今年它在法国第戎的勃艮第中心举行（2019 年 5 月 20-24 日，由 INSERM UMR1231，UBFC 组织），那里吃饱参与者强调了将细胞核视为协调复制、转录和核运输的特化胶体区室中心的重要性。