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Impact of Zumba on Cognition and Quality of Life is Independent of APOE4 Carrier Status in Cognitively Unimpaired Older Women: A 6-Month Randomized Controlled Pilot Study.
American Journal of Alzheimer's Disease and other Dementias ( IF 2.7 ) Pub Date : 2019-08-11 , DOI: 10.1177/1533317519868370
Cynthia M Stonnington 1 , Janina Krell-Roesch 2 , Dona E C Locke 1 , Joseph G Hentz 3 , Amylou C Dueck 3 , Yonas E Geda 1, 2, 4 , Pierre N Tariot 5 , Richard J Caselli 4
Affiliation  

OBJECTIVE To investigate the association of a 6-month Zumba intervention with cognition and quality of life among older cognitively unimpaired apolipoprotein ∊4 (APOE4) carrier and noncarrier women. METHODS Fifty-three women were randomly assigned to either twice-weekly Zumba group classes or maintenance of habitual exercise (control group) for 6 months. At baseline, 3, and 6 months, all participants underwent neuropsychological, physical activity, and quality-of-life assessments. RESULTS Overall, neuropsychological test scores and level of physical activity did not differ between intervention and control groups at any time. However, compared to the control group, quality of life was higher at 3 months, and visuospatial working memory and response inhibition improved more in the intervention group by 6 months. Apolipoprotein ∊4 status did not affect the results. DISCUSSION Zumba may strengthen performance on visuospatial working memory among cognitively unimpaired older women but this needs to be tested in a larger clinical trial.

中文翻译:


在认知未受损的老年女性中,尊巴舞对认知和生活质量的影响与 APOE4 携带状态无关:一项为期 6 个月的随机对照试点研究。



目的 调查 6 个月的 Zumba 干预与认知未受损的老年载脂蛋白∊4 (APOE4) 携带者和非携带者女性的认知和生活质量之间的关系。方法 53 名女性被随机分配到每周两次的 Zumba 团体课程或维持习惯运动(对照组)6 个月。在基线、3 个月和 6 个月时,所有参与者都接受了神经心理学、身体活动和生活质量评估。结果 总体而言,干预组和对照组之间的神经心理学测试分数和体力活动水平在任何时间都没有差异。然而,与对照组相比,干预组在 3 个月时的生活质量更高,并且在 6 个月时干预组的视觉空间工作记忆和反应抑制改善更多。载脂蛋白∊4状态不影响结果。讨论 尊巴舞可能会增强认知未受损的老年女性的视觉空间工作记忆表现,但这需要在更大规模的临床试验中进行测试。
更新日期:2019-11-01
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