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Cutaneous infection by Phaeoacremonium parasiticum.
Revista Iberoamericana de Micología ( IF 1.5 ) Pub Date : 2019-03-08 , DOI: 10.1016/j.riam.2018.10.003
Mariana J Fernandez-Pittol 1 , Izaskun Alejo-Cancho 1 , Elisa Rubio 1 , Miriam López 1 , Adriana García 2 , José Manuel Mascaro 3 , Francesc Marco 1 , Jordi Vila 1 , Jorge Puig de la Bellacasa 1
Affiliation  

Background

Phaeoacremonium parasiticum is considered a rare infectious agent that is part of a heterogeneous group of fungi causing phaeohyphomycosis. This organism is capable of producing subcutaneous infections, eumycetomas, osteomyelitis, arthritis, myositis and also disseminated diseases, such as fungemia and endocarditis.

Case report

We describe a case of cutaneous infection by P. parasiticum in a kidney transplant patient. The identification of this microorganism was performed by microbiological and histopathological studies and confirmed with the sequence of the gene encoding β-tubulin and a real time panfungal PCR targeting 18S ribosomal RNA gene. The microorganism was correctly identified by phenotypic and molecular methods. The patient was treated with oral antifungal therapy and a debulking surgery and evolved without any complication.

Conclusions

The diagnosis of this infection is difficult and usually affects kidney transplant patients, but the reasons of this association are still unknown.



中文翻译:

副产白囊藻的皮肤感染。

背景

寄生副球菌被认为是一种罕见的传染性病原,是引起细菌性真菌病的异质真菌群的一部分。该生物体能够产生皮下感染,杜鹃花瘤,骨髓炎,关节炎,肌炎以及诸如真菌病和心内膜炎之类的传播疾病。

案例报告

我们描述了在肾脏移植患者中由寄生疟原虫引起的皮肤感染的情况。通过微生物学和组织病理学研究对该微生物进行鉴定,并用编码β-微管蛋白的基因序列和靶向18S核糖体RNA基因的实时泛真菌PCR进行确认。通过表型和分子方法正确鉴定了微生物。该患者接受了口服抗真菌治疗和大型手术,并且没有任何并发​​症地发展。

结论

这种感染的诊断很困难,通常会影响肾移植患者,但是这种关联的原因仍然未知。

更新日期:2019-03-08
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