PURPOSE To provide an overview for radiologists of the systemic agents used in the treatment of advanced epithelial ovarian cancer (EOC) and their associated toxicities. RESULTS EOC is a common gynecological malignancy, with the majority of patients presenting with advanced stage disease at the time of diagnosis. Although primary cytoreductive surgery and chemotherapy are the principal treatments for EOC, recurrence rates of disease remain high. As several molecular targeted therapies have been developed in the last decade, various novel agents have shown efficacy in the treatment of advanced EOC. Advanced EOC will be discussed by outlining the relevant radiological features of toxicities. CONCLUSION Knowledge of the systemic therapies utilized in the treatment of advanced EOC and their associated radiological features is critical in diagnostic image interpretation.

中文翻译：

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与晚期卵巢上皮癌的全身治疗相关的影像学发现概述。

目的为放射科医生提供用于治疗晚期上皮性卵巢癌（EOC）的全身性药物及其相关毒性的概述。结果EOC是常见的妇科恶性肿瘤，大多数患者在诊断时出现晚期疾病。尽管原发性细胞减少手术和化学疗法是EOC的主要治疗方法，但疾病的复发率仍然很高。在过去的十年中，随着几种分子靶向疗法的发展，各种新型药物已显示出治疗晚期EOC的功效。将通过概述毒性的相关放射学特征来讨论高级EOC。