BACKGROUND Several recent studies have examined the positive effects of physical exercise and equilibrium on individuals with neurodegenerative diseases. OBJECTIVES In this sense, this study based on an experimental design, tested whether global postural reeducation (GPR) can affect equilibrium and cognition, life quality, and psychological symptoms of patients with Alzheimer's disease (AD). METHODS One hundred thirty-five participants with mild and moderate AD diagnosis were assigned to 2 groups: experimental group (EG, n = 90) and control group (CG, n = 45). The GPR therapy was implemented in the EG for 6 months, while both groups underwent neuropsychological assessments prior and after the 6-month period. RESULTS According to the repeated measures of analysis of variance, significant differences between groups were found at the 6-month follow-up period, in benefit of the EG such as Mini-Mental State Examination (P = .000), Geriatric Depression Scale (P = .000), Neuropsychiatric Inventory (P = .000), quality of life in AD/patient (P = .000), quality of life in AD/caregivers (P = .000), Barthel index (P = .000), and Tinetti Scale (P = .000), while the CG showed a low performance in the neuropsychological tests. CONCLUSIONS We suggest that GPR is a therapeutic option, which can improve the psychological, physical, and cognitive aspects of patients with AD.

中文翻译：

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关于阿尔茨海默病患者认知方法的全球姿势再教育实验性试点研究。


背景技术最近的几项研究探讨了体育锻炼和平衡对患有神经退行性疾病的个体的积极影响。目的 从这个意义上说，本研究基于实验设计，测试了整体姿势再教育（GPR）是否可以影响阿尔茨海默病（AD）患者的平衡和认知、生活质量和心理症状。方法 135 名患有轻度和中度 AD 诊断的参与者被分为 2 组：实验组（EG，n = 90）和对照组（CG，n = 45）。 GPR 治疗在 EG 中实施了 6 个月，两组在 6 个月之前和之后都接受了神经心理学评估。结果 根据方差分析的重复测量，在 6 个月的随访期间发现组间存在显着差异，这得益于简易精神状态检查 (P = .000)、老年抑郁量表 (P = .000)、老年抑郁量表 ( P = .000)、神经精神问卷 (P = .000)、AD/患者的生活质量 (P = .000)、AD/护理人员的生活质量 (P = .000)、Barthel 指数 (P = .000) ）和 Tinetti 量表（P = .000），而 CG 在神经心理学测试中表现不佳。结论 我们认为 GPR 是一种治疗选择，可以改善 AD 患者的心理、身体和认知方面。