Introduction

Given the high morbidity and mortality of stroke, there remains a demand for techniques that provide rapid and safe intervention while improving time to recanalization. The direct aspiration first pass technique (ADAPT) uses force and aspiration for clot removal without the aid of separators or retrievers. In this study, we compare the force and aspiration qualities of commercially available catheters.

Methods

Four different catheters with varying inner diameters were set up in a bench top model to test catheter tip pressure and flow rate. Catheter tip pressure was measured by attaching the catheter to a vacuum pressure gauge and an aspiration pump. The flow rate was calculated by measuring the volume of room temperature water aspirated through each catheter over a given time.

Results

The Microvention Sofia catheter generated the greatest tip force (21.32 g), and the Stryker AXS Catalyst 6 catheter generated the smallest tip force (15.88 g). The Penumbra ACE 068 catheter and Medtronic ARC catheter measured 20.87 g and 16.78 g respectively. The ACE 068 had highest rate of aspiration at 289 mL/min, and the Catalyst 6 catheter had the lowest rate at 214. The Microvention Sofia catheter had the second highest rate while the ARC had the third highest rate, measuring 285 mL/min and 256 mL/min, respectively.

Conclusions

When using the ADAPT technique, knowledge of the tip force and catheter flow rate of newer catheters with larger distal inner diameters may guide selection of aspiration catheters. While this study demonstrates differences in tip force and flow rate of different commercially available catheters, clinical translation will require further testing and evaluation.

中文翻译：

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急性缺血性卒中 ADAPT 技术中使用的导管的力和抽吸：台式分析

介绍

鉴于中风的高发病率和死亡率，仍然需要能够提供快速和安全干预同时缩短再通时间的技术。直接抽吸首次通过技术 (ADAPT) 使用力和抽吸来清除凝块，无需分离器或回收器的帮助。在这项研究中，我们比较了市售导管的力量和抽吸质量。

方法

在台式模型中设置了四种不同内径的不同导管，以测试导管尖端压力和流速。通过将导管连接到真空压力计和抽吸泵来测量导管尖端压力。通过测量在给定时间内通过每个导管吸入的室温水的体积来计算流速。

结果

Microvention Sofia 导管产生最大的尖端力 (21.32 g)，而 Stryker AXS Catalyst 6 导管产生最小的尖端力 (15.88 g)。Penumbra ACE 068 导管和 Medtronic ARC 导管分别测量 20.87 克和 16.78 克。ACE 068 的抽吸率最高，为 289 mL/min，Catalyst 6 导管的抽吸率最低，为 214。Microvention Sofia 导管的抽吸率第二高，而 ARC 的抽吸率第三高，为 285 mL/min 和分别为 256 毫升/分钟。

结论

使用 ADAPT 技术时，了解具有较大远端内径的新型导管的尖端力和导管流速可以指导抽吸导管的选择。虽然这项研究表明不同商用导管的尖端力和流速存在差异，但临床转化需要进一步的测试和评估。