Objective

To evaluate through differential diagnosis whether hypertrophic osteoarthropathy was present on an adult macaque skeleton.

Materials

Skeletal remains of a well-preserved adult macaque (Macaca) of unknown species curated by the archaeology department at University College London.

Methods

Macroscopic and radiographic evaluation of pathological lesions.

Results

Widespread bilateral and symmetrical periosteal new bone growth primarily affecting the limbs was observed.

Conclusion

A careful differential diagnosis of the lesions and comparison with previously published cases of hypertrophic osteoarthropathy among humans and non-humans suggests this animal displays a case of Hypertrophic osteoarthropathy.

Significance

Only been three reported cases of HOA in non-human primates have been reported, and all were apes. This study serves as the first reported case of HOA among non-hominoid simians, providing a detailed description of the skeletal lesions to aid future with paleopathological analyses.

Limitations

Small sample sizes for comparison and lack of context for this specimen limits discussion of the scope of this disease among non-human primates.

Suggestions for further research

Re-evaluate skeletal collections which have not been subject to recent osteological and pathological analysis.

中文翻译：

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成年猕猴肥厚性骨关节炎。

目的

通过鉴别诊断评估成年猕猴骨骼上是否存在肥厚性骨关节炎。

用料

伦敦大学学院考古部门精心策划的一种保存完好的未知物种成年猕猴（Macaca）的骨骼遗骸。

方法

病理病变的宏观和射线照相评估。

结果

观察到主要影响肢体的广泛的双侧和对称性骨膜新骨生长。

结论

对病变进行仔细的鉴别诊断，并与先前发表的人类和非人类肥厚性骨关节炎病例进行比较，这表明该动物表现出一例肥厚性骨关节炎。

意义

仅报告了三例非人类灵长类动物HOA病例，均为猿类。这项研究是非类人猿猴中首例报告的HOA病例，提供了骨骼病变的详细描述，以帮助将来进行古病理学分析。

局限性

用于比较的小样本量和缺乏本样本的上下文限制了非人类灵长类动物对该病范围的讨论。

进一步研究的建议

重新评估尚未经过近期骨病学和病理学分析的骨骼集合。