BACKGROUND The application of effective vaccines against pig cysticercosis and mass chemotherapy against pig cysticercosis and human taeniasis have shown the feasibility of interrupting the parasite's life cycle in endemic areas. METHODS A mathematical model that divides the population into susceptible, infected, and vaccinated individuals is formulated. The model is based upon the life cycle of the parasite. Computer numerical simulation experiments to evaluate the impact of pig vaccination under different vaccination schedules, and combined intervention strategies including pig vaccination and anthelmintic treatment against human taeniasis are carried out. RESULTS Vaccination against either pig cysticercosis or against human taeniasis will influence the transmission dynamics not only among vaccinees but also the dynamics of the other hosts as well. When the protective efficacy and/or the coverage rate is less than 100%, different mass interventions like vaccinating the pig population twice in combination with chemotherapeutic treatment against human taeniasis, the elimination of the infection in both pigs and humans can also be achieved. CONCLUSIONS Our mathematical model has the potential for planning, and designing effective intervention strategies including both mass vaccination and/or chemotherapeutic treatment to eliminate pig cysticercosis, human taeniasis and human neurocysticercosis. The model can be adapted to any given community with mild, moderate endemicity, or even in hyperendemic regions.

中文翻译：

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如何消除虫/囊尾osis病：猪疫苗接种和人用化学疗法（第2部分）。

背景技术针对猪囊尾病的有效疫苗的应用以及针对猪囊尾rc病和人的带状疱疹的大规模化学疗法已经显示出在流行地区中断寄生虫的生命周期的可行性。方法建立了将人群分为易感人群，感染人群和接种疫苗人群的数学模型。该模型基于寄生虫的生命周期。进行了计算机数值模拟实验，以评估不同疫苗接种方案下猪疫苗接种的影响，并进行了包括猪疫苗接种和驱虫药治疗人虫病在内的综合干预策略。结果针对猪囊尾rc病或人human虫病的疫苗接种不仅会影响疫苗接种者之间的传播动态，还会影响其他宿主的传播动态。当防护功效和/或覆盖率小于100％时，可以采取不同的大规模干预措施，例如对猪群进行两次疫苗接种，再结合针对人的ta虫病的化学疗法，可以消除猪和人的感染。结论我们的数学模型具有规划和设计有效干预策略的潜力，包括大规模疫苗接种和/或化学治疗，以消除猪囊尾rc病，人ta虫病和人神经囊尾rc病。该模型可以适用于任何具有轻度，中度流行，