We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 1217 Mexicans from the Mexico City Metropolitan Area living in the northern (N = 751), southern (N = 52), eastern (N = 79), western (N = 33), and central (N = 152) Mexico City, and rural communities (N = 150), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes include 11 Native American haplotypes. Admixture estimates revealed that the main genetic components are Native American (63.85 ± 1.55% by ML; 57.19% of Native American haplotypes) and European (28.53 ± 3.13% by ML; 28.40% of European haplotypes), and a less apparent African genetic component (7.61 ± 1.96% by ML; 7.17% of African haplotypes).

我们研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）基于PCR-SSP的等位基因来自居住在北部（N = 751），南部（N = 52），东部（N = 79），西部（N = 33）和中部的墨西哥城大都会地区的1217名墨西哥人（N = 152）墨西哥城和乡村社区（N = 150），以获取有关等位基因和单倍型频率的信息。我们发现，最常见的单倍型包括11个美国原住民单倍型。外加剂估计显示，主要的遗传成分是美洲原住民（按ML分类为63.85±1.55％；美国原住民单倍型为57.19％）和欧洲（按ML分类为28.53±3.13％；欧洲单倍型为28.40％），以及非洲遗传成分较少（按ML测得为7.61±1.96％；占非洲单倍型的7.17％）。