We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 88 Mexicans from the state of Querétaro living in the city of Querétaro (N = 45) and rural communities (N = 43), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in the state of Querétaro include seven Native American, two European and one Asian haplotype. Admixture estimates revealed that the main genetic components in the state of Querétaro are Native American (51.82 ± 4.42% by ML; 42.61% of Native American haplotypes) and European (48.18 ± 3.55% by ML; 46.02% of European haplotypes), with a virtually absent African genetic component (0.00 ± 4.25% by ML; 4.55% of African haplotypes).

我们研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）等位基因，通过基于PCR-SSP的方法，从居住在克雷塔罗市（N = 45）和农村社区（N = 43）的克雷塔罗州的88名墨西哥人中获得有关等位基因和单倍型频率的信息。我们发现，克雷塔罗州最常见的单体型包括7个美洲原住民，2个欧洲单体和1个亚洲单体型。混合物估计显示，克雷塔罗州的主要遗传成分是美洲原住民（按ML分类为51.82±4.42％;美国原住民单倍型为42.61％）和欧洲人（按ML分类为48.18±3.55％;欧洲单倍型为46.02％），其中几乎不存在非洲遗传成分（按ML计为0.00±4.25％；非洲单倍型的4.55％）。