Objectives: Coenzyme Q₁₀, incorporated in DOPC lyposomes or naturally present in liver bovine mitochondria or in human blood plasma, was reacted with nitrogen dioxide ^•NO₂ or with a ^•NO/^•NO₂ mixture.

Methods and Results: The reaction course was monitored by Electron Paramagnetic Resonance (EPR) spectroscopy and in all cases the formation of a di-tert-alkyl nitroxide was observed, deriving from the addition of ^•NO₂ to one of the double bonds, most likely the terminal one, of the isoprenic chain. The rate constant for nitroxide formation was also determined by EPR spectroscopy and an initial rate of ca. 7 × 10⁻⁸M s⁻¹ was obtained.

中文翻译：

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内源辅酶Q10与一氧化氮及其代谢产物二氧化氮的反应

目标：掺入DOPC脂质体中或天然存在于肝牛线粒体或人血浆中的辅酶Q ₁₀与二氧化氮^• NO ₂或^• NO / ^• NO ₂混合物反应。

方法和结果：反应过程通过电子顺磁共振（EPR）光谱在所有情况下的二监测形成叔烷基氮氧化物，观察到，从添加的导出^• NO ₂到双键之一，最可能是异戊二烯链的末端。氮氧化物形成的速率常数也通过EPR光谱法测定，初始速率约为。获得7×10 ^-8 M s ^-1。