Introduction: As the five dimensions of the EQ-5D might be insensitive to some populations or conditions, adding one or more specific 'bolt-on dimensions', to the EQ-5D may improve its validity and relevance for those groups. Various bolt-on dimensions have been identified and tested the effect on the psychometric performance and utility measurement. Therefore, this systematic review was to review all bolt-on dimensions and report the results of those two effects. Areas covered: Twelve studies were identified through PubMed, Scopus, and Web of Sciences from inception to January 2019. The bolt-on dimensions generally improved the EQ-5D's psychometric performance when compared with the standard version. However, evidence is lacking about the impact of bolt-on dimensions on responsiveness, reliability and known-groups validity. Evidence was also mixed for adding a sleep dimension, while interpersonal relationships did not promote a significant improvement on utility measurement. Expert opinion: Adding bolt-on dimensions could enhance the discriminative power and utility measurement of the EQ-5D; however, careful investigation of the sleep and interpersonal relationships is required since the evidence did not support a significant improvement. Further investigation of the identified bolt-on dimensions on all of the psychometric performance and the incremental utility scores derived from TTO is greatly encouraged.

中文翻译：

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对EQ-5D描述性系统其他尺寸的开发和测试进行系统的审查。

简介：由于EQ-5D的五个维度可能对某些人群或条件不敏感，因此在EQ-5D上添加一个或多个特定的“螺栓固定维度”可能会提高其对这些人群的有效性和相关性。已经确定了各种固定尺寸，并测试了它们对心理测量性能和公用事业测量的影响。因此，这项系统的审查是审查所有螺栓固定尺寸并报告这两种效果的结果。涵盖的领域：从成立到2019年1月，通过PubMed，Scopus和Web of Sciences进行了12项研究。与标准版本相比，螺栓固定的尺寸通常可以改善EQ-5D的心理测量性能。但是，缺乏有关附加尺寸对响应性，可靠性和已知群体有效性的影响的证据。增加睡眠维度的证据也好坏参半，而人际关系并未促进效用测量的显着改善。专家意见：增加螺栓固定尺寸可以增强EQ-5D的辨别力和实用性；但是，由于证据不能支持显着改善，因此需要仔细研究睡眠和人际关系。鼓励进一步研究确定的所有心理行为表现上的固定尺寸以及从TTO得出的递增效用得分。但是，由于证据不能支持显着改善，因此需要仔细研究睡眠和人际关系。鼓励进一步研究确定的所有心理行为表现上的固定尺寸以及从TTO得出的递增效用得分。但是，由于证据不能支持显着改善，因此需要仔细研究睡眠和人际关系。鼓励进一步研究确定的所有心理行为表现上的固定尺寸以及从TTO得出的递增效用得分。