We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 98 Mexicans from the state of Quintana Roo living in the city of Cancún (N = 48) and rural communities (N = 50), to obtain information regarding allelic and haplotypic frequencies and their linkage disequilibrium. We found that the most frequent haplotypes in Quintana Roo include ten Native American and two European haplotypes. Admixture estimates revealed that the main genetic components in Quintana Roo are Native American (80.85 ± 3.70% by ML; 60.20% of Native American haplotypes) and European (15.19 ± 14.25% by ML; 26.02% of European haplotypes), and a less prominent African genetic component (3.96 ± 10.75% by ML; 6.63% of African haplotypes).

我们研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）基于PCR-SSP的等位基因，从居住在坎昆市（N = 48）和农村社区（N = 50）的金塔纳罗奥州州的98名墨西哥人中获得有关等位基因和单倍型频率及其连锁不平衡的信息。我们发现金塔纳罗奥州最常见的单倍型包括十个美洲原住民和两个欧洲单倍型。外加剂的估计表明，金塔纳罗奥州的主要遗传成分是美洲原住民（按ML分类为80.85±3.70％；美国原住民单倍型为60.20％）和欧洲人（按ML分类为15.19±14.25％；欧洲单倍型为26.02％），但不那么突出非洲遗传成分（按ML的比例为3.96±10.75％；非洲单倍型的6.63％）。