We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 636 Mexicans from the state of Oaxaca living in the city of Oaxaca (N = 151) and rural communities (N = 485), to obtain information regarding allelic and haplotypic frequencies. We found that the 13 most frequent haplotypes in Oaxaca are all of putative Native American origin. Admixture estimates revealed that the main genetic components in the state of Oaxaca are Native American (73.12 ± 2.77% by ML; 61.52% of Native American haplotypes) and European (17.36 ± 2.07% by ML; 20.69% of European haplotypes), and a relatively high African genetic component (9.52 ± 0.88% by ML; 8.94% of African haplotypes).

我们通过基于PCR-SSP的打字方法研究了生活在瓦哈卡州瓦哈卡州（N = 151）的墨西哥人中的HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）等位基因和农村社区（N = 485），以获取有关等位基因和单倍型频率的信息。我们发现，瓦哈卡州13种最常见的单倍型都是假定的美国原住民血统。外加剂估计显示，瓦哈卡州的主要遗传成分是美洲原住民（按ML分类为73.12±2.77％;按美国原住民单倍型为61.52％）和欧洲按欧洲分类标准（按ML为17.36±2.07％;按欧洲单倍型为20.69％），以及相对较高的非洲遗传成分（按ML值则为9.52±0.88％；占非洲单倍型的8.94％）。