We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 122 Mexicans from the state of Hidalgo living in the city of Pachuca (N = 41) and rural communities (N = 81), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in Hidalgo include eight Native American and one European haplotypes. Admixture estimates revealed that the main genetic components in Hidalgo are Native American (58.93 ± 2.16% by ML; 54.51% of Native American haplotypes) and European (32.49 ± 2.88% by ML; 28.69% of European haplotypes), and a relatively high African genetic component (8.58 ± 0.93% by ML; 6.97% of African haplotypes).

我们通过基于PCR-SSP的分型方法研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）等位基因，来自居住在帕丘卡市（H = 41）的伊达尔戈州的122名墨西哥人和农村社区（N = 81），以获取有关等位基因和单倍型频率的信息。我们发现，伊达尔戈（Hidalgo）最常见的单倍型包括八种美洲原住民和一种欧洲单倍型。外加剂估计显示，伊达尔戈的主要遗传成分是美洲原住民（按ML分类为58.93±2.16％；美国原住民单倍型为54.51％）和欧洲（按ML分类为32.49±2.88％；欧洲单倍型为28.69％），以及相对较高的非洲人遗传成分（按ML值分别为8.58±0.93％;非洲单倍型的6.97％）。