We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 173 Mexicans from the state of Chiapas living in the city of Tuxtla Gutiérrez (N = 52) and rural communities (N = 121), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes in Chiapas include 12 Native American and one European haplotype. Admixture estimates revealed that the main genetic components in Chiapas are Native American (71.61 ± 0.58% by ML; 53.16% of Native American haplotypes) and European (26.39 ± 5.05% by ML; 25.86% of European haplotypes), and a less prominent African genetic component (2.00 ± 5.20% by ML; 9.77% of African haplotypes).

我们通过基于PCR-SSP的分型方法研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）等位基因，来自居住在TuxtlaGutiérrez市的恰帕斯州的173名墨西哥人（N = 52 ）和农村社区（N = 121），以获取有关等位基因和单倍型频率的信息。我们发现恰帕斯州最常见的单体型包括12个美洲原住民和1个欧洲单体型。外加剂估计显示，恰帕斯州的主要遗传成分是美洲原住民（按ML分类为71.61±0.58％；美国原住民单倍型为53.16％）和欧洲（按ML分类为26.39±5.05％；欧洲单倍型为25.86％），以及不太突出的非洲遗传成分（按ML值的2.00±5.20％；非洲单倍型的9.77％）。