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The Association of a Novel Identified VDR SNP With Prostate Cancer in African American Men.
Cancer Genomics & Proteomics ( IF 2.5 ) Pub Date : 2019-6-28 , DOI: 10.21873/cgp.20129
Mohammad R Daremipouran 1 , Desta Beyene 1 , Victor Apprey 2 , Tammey J Naab 3 , Olakunle O Kassim 4 , Robert L Copeland 1, 5 , Yasmine M Kanaan 1, 4
Affiliation  

Vitamin D receptor (VDR) is present in numerous cellular pathways and it has been suggested that VDR genetic variants influence individual susceptibility to prostate cancer. Also, analyses of single nucleotide polymorphisms (SNPs) in VDR revealed ethnicity-associated polymorphisms. The aim of this study was to identify VDR SNPs in African American men with and without prostate cancer.

中文翻译:

新型鉴定的VDR SNP与非裔美国人前列腺癌的关联。

维生素D受体(VDR)存在于许多细胞途径中,并且已表明VDR遗传变异会影响个体对前列腺癌的敏感性。而且,对VDR中的单核苷酸多态性(SNP)的分析显示了种族相关的多态性。这项研究的目的是鉴定患有和不患有前列腺癌的非洲裔美国男性中的VDR SNP。
更新日期:2020-08-21
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