Primary prostate lymphoma (PPL) is rare. This article reports a case of PPL by retrospective analysis of the clinical data and review of the literature, in an attempt to explore the diagnosis, treatment, and prognosis of this rare disease. The present case involves a male patient who came to our hospital for medical consultation of dysuria. Serum prostate-specific antigen (PSA) was not remarkable. Pelvic computed tomography (CT) scan suggested obvious enlargement of the prostate and a tumor in the prostate, but the tumor was not significantly enhanced on contrast-enhanced CT scan. Ultrasound suggested obvious enlargement of the prostate with multiple local low-density echoes and rich blood flow signals inside. Histopathology of prostate biopsy suggested prostate diffuse large B-cell lymphoma (DLBCL). The patient refused chemotherapy but agreed to receive radiotherapy. After radiotherapy, the tumor became smaller and the International Prostate Symptom Score (IPSS) score was reduced. Our experience, together with literature review, suggests that prostate puncture biopsy is an important method for the diagnosis of PPL, and imaging examination can assist the diagnosis. Radiotherapy is able to reduce the tumor volume and relieve the symptoms of urinary tract obstruction, and chemotherapy can help achieve a better therapeutic outcome.

中文翻译：

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原发性前列腺淋巴瘤：一例报道并文献复习。

原发性前列腺淋巴瘤（PPL）很少。本文通过对临床数据进行回顾性分析并进行文献回顾来报道一例PPL，以试图探索这种罕见疾病的诊断，治疗和预后。本案涉及一名男病人，他来我院接受排尿困难的医疗咨询。血清前列腺特异性抗原（PSA）不明显。骨盆计算机断层扫描（CT）扫描提示前列腺明显增大，前列腺中有肿瘤，但对比增强CT扫描未发现肿瘤明显增强。超声提示前列腺明显肿大，内部有多个局部低密度回声和丰富的血流信号。前列腺活检的组织病理学提示前列腺弥漫性大B细胞淋巴瘤（DLBCL）。病人拒绝化疗但同意接受放疗。放疗后，肿瘤变小，国际前列腺症状评分（IPSS）评分降低。我们的经验以及文献综述表明，前列腺穿刺活检是诊断PPL的重要方法，而影像学检查可以帮助诊断。放射疗法能够减少肿瘤体积并缓解尿路阻塞症状，而化学疗法可以帮助取得更好的治疗效果。影像学检查可以帮助诊断。放射疗法能够减少肿瘤体积并缓解尿路阻塞症状，而化学疗法可以帮助取得更好的治疗效果。影像学检查可以帮助诊断。放射疗法能够减少肿瘤体积并缓解尿路阻塞症状，而化学疗法可以帮助取得更好的治疗效果。