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"In sickness and in health" - how neutrophil extracellular trap (NET) works in infections, selected diseases and pregnancy.
Journal of Inflammation ( IF 4.4 ) Pub Date : 2019-06-28 , DOI: 10.1186/s12950-019-0222-2
Paulina Niedźwiedzka-Rystwej 1 , Weronika Repka 2 , Beata Tokarz-Deptuła 1 , Wiesław Deptuła 3
Affiliation  

The discovery of the NET network (neutrophil extracellular trap) has revolutionized the perception of defense mechanisms used by neutrophils in infections and non-infectious states, as this mechanism proves the complexity of the ways in which neutrophils can act in the organism. The paper describes the NET network and its participation in bacterial, viral, fungal and parasitic infections, both in a positive and a negative aspect. In addition, attention was paid to the participation of NETs in the course of autoimmune diseases, cancer, as well as its impact on pregnancy and fertility in mammals.

中文翻译:


“在疾病和健康中”——中性粒细胞胞外陷阱 (NET) 在感染、特定疾病和妊娠中的作用。



NET网络(中性粒细胞胞外陷阱)的发现彻底改变了中性粒细胞在感染和非感染状态下使用的防御机制的认知,因为这种机制证明了中性粒细胞在生物体中作用方式的复杂性。该论文从积极和消极的方面描述了 NET 网络及其在细菌、病毒、真菌和寄生虫感染中的参与。此外,NETs参与自身免疫性疾病、癌症的发病过程及其对哺乳动物妊娠和生育的影响也受到关注。
更新日期:2020-04-22
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