PURPOSE This study examined the prevalence of financial toxicity (FT) and associated factors among urologic cancer patients. The association between FT and health-related quality of life (HRQoL) was also investigated. METHODS A total of 429 respondents diagnosed with urologic cancers (prostate cancer, bladder and renal cancer) from Sarawak General Hospital and Subang Jaya Medical Centre in Malaysia were interviewed using a structured questionnaire. Objective and subjective FT were measured by catastrophic health expenditure (healthcare-cost-to-income ratio greater than 40%) and the Personal Financial Well-being Scale, respectively. HRQoL was measured with the Functional Assessment of Cancer Therapy - General 7 Items scale. RESULTS Objective and subjective FT were experienced by 16.1 and 47.3% of the respondents, respectively. Respondents who sought treatment at a private hospital and had out-of-pocket health expenditures were more likely to experience objective FT, after adjustment for covariates. Respondents who were female and had a monthly household income less than MYR 5000 were more likely to experience average to high subjective FT. Greater objective FT (OR = 2.75, 95% CI 1.09-6.95) and subjective FT (OR = 4.68, 95% CI 2.63-8.30) were associated with poor HRQoL. CONCLUSIONS The significant association between both objective and subjective FT and HRQoL highlights the importance of reducing FT among urologic cancer patients. Subjective FT was found to have a greater negative impact on HRQoL.

中文翻译：

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中等偏上收入国家泌尿外科癌症患者的财务毒性及其与健康相关的生活质量的关系。

目的这项研究检查了泌尿外科癌症患者的财务毒性（FT）和相关因素的患病率。FT和健康相关的生活质量（HRQoL）之间的关联也进行了调查。方法使用结构化问卷对来自马来西亚砂拉越综合医院和梳邦再也医学中心的429名被诊断为泌尿科癌症（前列腺癌，膀胱癌和肾癌）的受访者进行了访谈。客观和主观金融时报分别通过灾难性的医疗支出（医疗保健成本收入比大于40％）和个人财务状况量表来衡量。HRQoL用“癌症治疗的功能评估-总体7项目”量表进行测量。结果分别有16.1％和47.3％的受访者经历了客观和主观FT。在对协变量进行调整后，在私立医院寻求治疗且医疗费用自付的受访者更有可能经历客观FT。女性且家庭月收入低于5000马币的受访者更有可能经历中等至较高的主观FT。较高的客观FT（OR = 2.75，95％CI 1.09-6.95）和主观FT（OR = 4.68，95％CI 2.63-8.30）与较差的HRQoL相关。结论客观和主观FT与HRQoL之间的显着相关性凸显了降低泌尿外科癌症患者FT的重要性。发现主观FT对HRQoL有更大的负面影响。女性且家庭月收入低于5000马币的受访者更有可能经历中等至较高的主观FT。较高的客观FT（OR = 2.75，95％CI 1.09-6.95）和主观FT（OR = 4.68，95％CI 2.63-8.30）与较差的HRQoL相关。结论客观和主观FT与HRQoL之间的显着相关性凸显了降低泌尿外科癌症患者FT的重要性。发现主观FT对HRQoL有更大的负面影响。女性且家庭月收入低于5000马币的受访者更有可能经历中等至较高的主观FT。较高的客观FT（OR = 2.75，95％CI 1.09-6.95）和主观FT（OR = 4.68，95％CI 2.63-8.30）与较差的HRQoL相关。结论客观和主观FT与HRQoL之间的显着相关性凸显了降低泌尿外科癌症患者FT的重要性。发现主观FT对HRQoL有更大的负面影响。结论客观和主观FT与HRQoL之间的显着相关性凸显了降低泌尿外科癌症患者FT的重要性。发现主观FT对HRQoL有更大的负面影响。结论客观和主观FT与HRQoL之间的显着相关性凸显了降低泌尿外科癌症患者FT的重要性。发现主观FT对HRQoL有更大的负面影响。