A sensitive and accurate simultaneous continuous analysis for six arsenic species including arsenobetaine (AsB), arsenocholine (AsC), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), arsenite (), and arsenate () has been developed by high performance liquid chromatography with inductively coupled plasma mass spectrometry (HPLC-ICP-MS). An anion-exchange column of Hamilton PRP-X100 (Switzerland) was applied for separation of the six arsenic species with gradient elution of 1.25 mmol/L Na₂HPO₄ and 11.0 mmol/L KH₂PO₄ as the mobile phase A and 2.5 mmol/L Na₂HPO₄ and 22.0 mmol/L KH₂PO₄ as the mobile phase B. The linearity ranges for AsB, AsC, MMA, DMA, , and were between 0.5 and 50.0 μg/L, and the detection limits of the six arsenic species were all within 0.01–0.35 ng/L. The relative standard deviations (RSDs) were within 2.26–3.68% and the recovery rates of samples ranged from 95 to 103%. The proposed method was applied for the arsenic speciation analysis of sediment pore-water samples, which were taken from the supernatant after centrifugation and filtration.

中文翻译：

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高效液相色谱-电感耦合等离子体质谱法测定痕量砷。

通过高效液相色谱法开发了灵敏且准确的连续连续分析方法，可对包括砷甜菜碱（AsB），砷中毒胆碱（AsC），一甲基砷酸（MMA），二甲基砷酸（DMA），亚砷酸盐（）和砷酸盐（）的六种砷进行分析。电感耦合等离子体质谱（HPLC-ICP-MS）。汉密尔顿PRP-X100（瑞士）的阴离子交换柱用于分离六种砷，其中梯度洗脱液为1.25 mmol / L Na ₂ HPO ₄和11.0 mmol / L KH ₂ PO ₄作为流动相A和2.5 mmol / L Na ₂ HPO ₄和22.0 mmol / L KH ₂ PO ₄作为流动相B.的线性范围为ASB，ASC，MMA，DMA， ，和分别为0.5和50.0之间μ克/升，和六个砷物质的检出限为所有内0.01-0.35纳克/升。相对标准偏差（RSD）在2.26-3.68％之间，样品的回收率在95％至103％之间。该方法适用于沉淀孔水样品的砷形态分析，该样品取自离心过滤后的上清液。