Despite a multitude of commercially available multi-electrode array (MEA) systems that are each capable of rapid data acquisition from cultured neurons or slice cultures, there is a general lack of available analysis tools. These analysis gaps restrict the efficient extraction of meaningful physiological features from data sets, and limit interpretation of how experimental manipulations modify neural network activity. Here, we present the development of a user-friendly, publicly-available software called MEAnalyzer. This software contains several spike train analysis methods including relevant statistical calculations, periodicity analysis, functional connectivity analysis, and advanced data visualizations in a user-friendly graphical user interface that requires no coding from the user. Widespread availability of this user friendly and mathematically advanced program will stimulate and enhance the use of MEA technologies.

中文翻译：

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MEAnalyzer-用于多电极阵列的尖峰训练分析工具。

尽管有许多商业上可用的多电极阵列（MEA）系统，每个系统都能够从培养的神经元或切片培养物中快速获取数据，但普遍缺乏可用的分析工具。这些分析差距限制了从数据集中有效提取有意义的生理特征的能力，并限制了对实验操作如何修改神经网络活动的解释。在这里，我们介绍了一种名为MEAnalyzer的用户友好型公共可用软件的开发。该软件包含多种峰值序列分析方法，包括相关的统计计算，周期性分析，功能连接性分析以及用户友好的图形用户界面中的高级数据可视化，无需用户编码。