Forkhead box M1 ( FOXM 1) transcription factor is a key oncogenic driver of aggressive human meningioma progression,Neuropathology and Applied Neurobiology

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Forkhead box M1 ( FOXM 1) transcription factor is a key oncogenic driver of aggressive human meningioma progression
Neuropathology and Applied Neurobiology ( IF 4.0 ) Pub Date : 2019-07-05 , DOI: 10.1111/nan.12571
H Kim ₁ , K-J Park ₁ , B-K Ryu ₁ , D-H Park ₁ , D-S Kong ₂ , K Chong ₁ , Y-S Chae ₃ , Y-G Chung ₁ , S I Park _{4,

5,

6,

7} , S-H Kang ₁

Affiliation

Aggressive meningioma remains incurable with neither chemo‐ nor targeted therapies proven effective, largely due to unidentified genetic alterations and/or aberrant oncogenic pathways driving the disease progression. In this study, we examined the expression and function of Forkhead box M1 (FOXM1) transcription factor during meningioma progression.

中文翻译：

Forkhead box M1 (FOXM 1) 转录因子是侵袭性人类脑膜瘤进展的关键致癌驱动因素

侵袭性脑膜瘤仍然无法治愈，无论是化学疗法还是靶向疗法都证明是有效的，这主要是由于未确定的基因改变和/或驱动疾病进展的异常致癌途径。在这项研究中，我们检查了 Forkhead box M1 (FOXM1) 转录因子在脑膜瘤进展过程中的表达和功能。

更新日期：2019-07-05

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