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Urinary cysteinyl leukotriene E4 level and therapeutic response to montelukast in children with mild obstructive sleep apnea.
Asian Pacific Journal of Allergy and Immunology ( IF 5 ) Pub Date : 2017-4-2 , DOI: 10.12932/ap0879
Kanokkarn Sunkonkit 1 , Suchada Sritippayawan 1 , Montida Veeravikrom 2 , Jitladda Deerojanawong 1 , Nuanchan Prapphal 1
Affiliation  

Antileukotriene has been used for alleviating disease severity in children with adenotonsillar hypertrophy (ATH) and mild obstructive sleep apnea (OSA). Previous study showed the relationship between urinary cysteinyl leukotriene E₄ (uLTE₄) level and therapeutic response to montelukast in asthmatic adults. However, this relationship has never been investigated in pediatric OSA.

中文翻译:

轻度阻塞性睡眠呼吸暂停患儿的尿半胱氨酸白三烯E4水平和对孟鲁司特的治疗反应。

抗白三烯已被用于减轻患有腺扁桃体肥大(ATH)和轻度阻塞性睡眠呼吸暂停(OSA)的儿童的疾病严重程度。先前的研究表明,哮喘的成年人尿半胱氨酰白三烯E₄(uLTE₄)水平与对孟鲁司特的治疗反应之间存在相关性。但是,这种关系从未在儿科OSA中进行过研究。
更新日期:2020-08-21
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